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Human safety data on long continuous use is limited, so capping exposure is reasonable caution
Sclerosing agents tested included 1% bichloride of mercury, 48 30% sodium chloride and 50% grape sugar, 49, 50 30% sodium salicylate, 51 50% to 60% calorose, 52, 53 and SM
As with other substance use disorders, both genetic (such as mutations in the opioid receptor gene (10)) and environmental factors (such as exposure to trauma), contribute to the risk of developing opioid use disorder.(11) Ready access to prescription opioid, heroin, and fentanyl have all contributed to the current opioid epidemic
University of California, Los Angeles
