Over the past decade, studies have shown GLP-1 receptor agonists like semaglutide (Ozempic or Wegovy) reduce food seeking, but also alcohol intake, cocaine reward, nicotine self-administration, and relapse-like behavior spanning multiple drug classes
Overall, it's a great supplement that delivers on its promises
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In a randomized controlled trial involving obese individuals, tesofensine treatment led to significant reductions in body weight and improved metabolic parameters compared to placebo
Roughly 40% of participants taking semaglutide reported no heavy drinking days during the final month of the trial, compared to just 20% on placebo
This increased risk has led researchers and regulators to urge caution for patients with existing eye disease