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3-AB can have off-target effects and less potency, making it mainly a research tool rather than a therapeutic agent 177
10.1016/j.ymben.2010.03.004 87 OBrienR
COSTA.IT 295 trial showed that although pioglitazone had no significant difference in total cardiovascular deaths compared with sulfonylureas in primary ASCVD diabetic patients, it significantly reduced the risk of ischemic cardiovascular events by 33%
(PubMed) Suksomboon N, Poolsup N, Juanak N
The base form (crack or freebase) is typically smoked Cocaine is rapidly metabolized in the liver and blood into two primary, inactive metabolites: benzoylecgonine and ecgonine methyl ester (which are targets for drug analysis)
doi:10.1086/666606 4 Wood JM, et al
