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Efficacy and Safety of a Novel Triple-Agonist (GLP-1/GIP/Glucagon) Retatrutide in People With Type 2 Diabetes: A Phase 2 Randomised Clinical Trial
Archived from the original on 28 September 2024
Reported side effects include: Other side effects reported include reduced appetite (also a side effect of the drug), tiredness, and skin sensitivity
When choosing among them, factors such as glycemic efficacy, weight effects and patient preferences may take precedence over concerns about major differences in [GI] risk. She added clinicians should continue to monitor for GI symptoms, particularly early in treatment, as these events, while uncommon, remain more frequent than with some other diabetes drug classes. According to Alkabbani and colleagues, recent trials revealed that dulaglutide (Trulicity, Eli Lilly), semaglutide (Ozempic/Wegovy, Novo Nordisk) and tirzepatide (Zepbound, Eli Lilly) increased the risk for mild to serious GI adverse events like pancreatitis, constipation, nausea, vomiting and biliary disease
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