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Since the pancreas has abundant GAD, a direct immunological destruction occurs in the pancreas and the patients will have diabetes mellitus

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As a more potent peptide, side effects can be more pronounced, making site selection strategically important

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Gut 40 , 597601 (1997)

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Early clinical experiments showed that a continuous intravenous infusion of native GLP-1 could nearly normalize blood glucose levels in people with type 2 diabetes ( [41] ) ( [39] )

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Importantly, apoptotic cell death was attenuated with 50 M QVD, indicating that the cell death is caspase mediated

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