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Telencephalon Moderate density of GLP-1R is expressed in both the cell bodies and fibers of the NAc shell and core (Mietlicki-Baase et al., 2014)

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Food and Drug Administration for chronic weight management in adults with obesity, or adults who are overweight and have at least one weight-related condition such as high blood pressure or high cholesterol. Wegovy contains semaglutide , the same active ingredient found in Ozempic, a medication approved for the treatment of type 2 diabetes. The difference between Wegovy and Ozempic isnt the drug itselfits the dosage, indication, and prescribing guidelines . Because semaglutide affects appetite regulation, digestion, and insulin-related pathways, Wegovy often shows up in diabetes conversations even though it is not prescribed specifically to treat diabetes

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Although the SUSTAIN-6 trial illustrates that diabetic patients taking subcutaneous semaglutide are not at increased risk of developing acute pancreatitis, clinicians may need to consider discontinuation of this GLP-1 receptor agonist in patients who present with Acute Pancreatitis while taking this class of medication, particularly if they have other risk factors for acute pancreatitis