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However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)

In the freeze-dried material, the basic chemical composition was assessed, the concentration of total iodine and total nitrogen as well as micro- and macroelements were determined

The benefit of this is that this higher dose can be injected in one shot and the benefits of B12 supplementation may be felt sooner

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Research also discusses effects on growth-factor signaling and collagen organization, which are relevant to connective tissue remodeling