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T., Gokce, S., Aydin, S

GLP-1 in Obesity: Why Weight Loss Is So Powerful GLP-1RAs reduce body weight through multiple synergistic mechanisms: Appetite suppression Delayed gastric emptying Reduced reward-driven eating Central hypothalamic satiety signalling Reduced caloric intake Hypothalamic Action GLP-1 stimulates satiety neurons: POMC/CART neurons And suppresses hunger neurons: NPY/AgRP neurons This creates sustained appetite reduction and clinically meaningful weight loss

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a gradual taper (if medically appropriate) may ease the adjustment

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As Daniell started experiencing weight gain, she also started experiencing symptoms of extreme hormonal imbalance, to the point where she needed to be on birth control in order to achieve regular periods