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It also states that if theres inconsistency with the test result and the patients reported symptoms, the patient should still be treated with replacement B12 to prevent any potential irreversible damage

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Myeloproliferative neoplasms (such as polycythaemia vera or chronic myeloid leukaemia) and acute leukaemias can increase B12-binding proteins (transcobalamins), raising total serum B12