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The study highlights that PEGylated PLGA nanoparticles, could offer a promising alternative for the safe delivery of tolcapone, maintaining its therapeutic effects while significantly reducing associated hepatotoxicity 129

461 Conversely, interventions such as caloric restriction enhance autophagy, improve remyelination, and reduce disease severity in relapsing-remitting MS, emphasizing its therapeutic potential when properly modulated

To provide a comparison, several studies have researched the anabolic potential of IGF-1

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Reactive protein

Yet, the mechanisms they employ have complimenting approaches in managing metabolic health