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Description

In clinical settings, factors such as tumor vascular density, stromal composition, interstitial fluid pressure, and patient-specific variability can significantly limit the predictability and magnitude of EPR-based delivery [182]

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A further increase in D-HIS to 800 g/ml returned the GSH close to the control level and it was noted that specific growth rate of cultures and OD 600 after 24 h were significantly decreased at this D-HIS concentration (Fig

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