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The human glutathione transferase P1-1 specific inhibitor TER 117 designed for overcoming cytostatic-drug resistance is also a strong inhibitor of glyoxalase I

Doses above 1mg increase the incidence of gastrointestinal symptoms and theoretically elevate mechanism-based risks like phosphate dysregulation, though no formal dose-response safety study has been published

VMAT1 is expressed in peripheral neuroendocrine cells (adrenal chromaffin cells, interneurons of sympathetic ganglia, and enterochromaffin cells that store serotonin in the GI tract)

For years, I watched patients who desperately needed glutathione support autoimmune patients, toxic overload cases, people with chronic inflammation struggle with the options

If your glutathione is in powder form, ensure the flavors complement each other, but there is no chemical reason they cannot be mixed