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However, studies have shown that antioxidant approaches, including anti-neuroinflammatory and neuroprotective agents, may have therapeutic efficacy in the treatment of PD ( The interplay between mitochondrial function and GSH is especially critical in PD

By blocking NNMT, 5-Amino-1MQ drives several metabolic benefits: Boosts NAD Levels Inhibiting NNMT preserves more nicotinamide for NAD synthesis, leading to enhanced mitochondrial function, increased cellular energy output, and activation of sirtuins , the proteins involved in longevity and DNA repair

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H.et al (2022)

The body tightly regulates B12 absorption through intrinsic factor, a protein produced in the stomach that binds to B12 and facilitates its uptake in the terminal ileum

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