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Biochim Biophys Acta (BBA)-Molecular Cell Res (2020) 1867(4):118649
In adult patients with T2DM, intramuscular injections (eight to 10 loading injections of 1,000 g each over one to two weeks, followed by monthly 1,000-g injections) or oral vitamin B12 1,000 to 2,000 g daily are sufficient to correct vitamin B12 deficiency.9 Patients should be monitored for response to therapy
For higher doses, the 1ml reconstitution may be more practical
For example: Gastric Sleeve and Gastric Bypass: 500 mcg per day is typically advised
Absorption The absolute bioavailability of sitagliptin is approximately 87%
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