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Surgery carries its own risks and is typically only recommended for symptomatic gallstones
Failure to do so may result in a more pronounced stinging sensation and increased likelihood of injection site reactions
Research has documented lower circulating MOTS-c in patients with obesity, type 2 diabetes, and insulin resistance, and higher levels in populations with healthy metabolic aging
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Consequently, cell-based therapeutic paradigms have shifted from direct neuronal replacement toward metabolic rescue
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