Heart palpitations and muscle spasms or cramps
Active or past cancer, pregnancy or breastfeeding, or uncontrolled diabetes
For something a bit more specific, like joint pain, weight loss, or general exercise goals, taking collagen around your workouts (e.g., in a pre-workout smoothie 30 to 60 minutes before) may help support collagen synthesis in your connective tissues
Patients with genetic predispositions toward insulin resistance (variants like FTO rs9939609) or GLP-1 receptor sensitivity (GLP1R rs6923761) may experience different metabolic responses to treatment, affecting which biomarkers shift during GLP-1 use
It's worth being ready for it
This supplement was the priciest one on our list, at $1.33 per serving, but we feel that because it was also the supplement with the highest BCAA content on our list (at 8 g of BCAAs per serving), it's worth the additional cost