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Ghanem, H., Glina, S., Assalian, P
Host cells contain an accessory plasmid that encodes a protease-activated T7 RNA polymerase (RNAP), which transcribes gIII in response to protein cleavage, thereby linking phage propagation to protease activity
Transporter assays for SGLT1 (Sodium-GLUcose Transporter 1) and GLUT2 (Glucose Transporter 2) are also available
Additionally, cardiovascular and metabolic benefits observed at therapeutic doses might be partially retained at lower doses, though this remains speculative without dedicated dose-finding studies
The peak plasma concentration the point at which the medication is most active in the body typically occurs within 8 to 72 hours post-injection, depending on the individual