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Clinically, this synergy is relevant in immune dysfunction, chronic fatigue, skin aging, cardiovascular risk, and metabolic stress
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Nevertheless, compounds that stimulate mitochondrial oxidative metabolism, including thyroid hormone receptor agonists20, ligands for nuclear receptors that control the expression of mitochondrial genes21 and inhibitors of mitochondrial pyruvate import22, have shown efficacy in the treatment of NASH
Following the application of the extract at concentrations of 250 mg/L and 500 mg/L, no damage was observed in the roots of the AVE 1 and AVE 2 groups, similar to the control group (Table 6 and Fig
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