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In the kidneys, intermediary metabolism and related cellular functions such as mitochondrial function play an essential role in the development of acute kidney injury and chronic kidney disease 13,14
More supplemental indications for GLP-1s could in the offing in the chronic kidney disease area as well as non-alcoholic steatohepatitis, or NASH
However, clinical consideration is still required
In light of these findings, it may be necessary to reexamine the current RDAs for adequate Vitamin B6 status in many population groups especially since MTHFR mutations affect B6 metabolism so significantly
And most importantly, does it actually work or is this another overhyped supplement promising results it cannot deliver
doi: 10.1227/00006123-198701000-00010 48 ZhangHYYangGHChenHJWeiBKeQGuoHet al
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