Supplements That Are Safe but may not be very helpful specifically to isotretinoin therapy These supplements are commonly asked about but dont help isotretinoin side effects: Collagen powders fine, but wont reduce dryness Protein powders safe Magnesium helps muscle cramps, not acne Vitamin C safe, but no proven benefit Iron only take if deficient Turmeric/curcumin generally safe but may interact with blood thinners Other topical therapies to help with isotretinoin side effects These arent supplements but are extremely effective for managing dryness: Urea-based moisturisers (510%) Excellent for flaking or sensitivity
PMID: 40460553 L-Glutathione reduced purchased from MedChemExpress
Data was self-reported by 526 surveyed customers who checked in with their provider on their third check-in between 11/1/24-10/1/25
Future large-scale studies incorporating multi-region sampling and functional validation of GSH pathwayrelated genes will be required to establish their clinical utility
It does this primarily by regulating nitric oxide, a molecule that controls how blood vessels expand and contract (Seiwerth et al., 2018)
This state, characterized by an imbalance between ROS production and elimination by the antioxidant system in favor of ROS formation, is termed oxidative stress (Sies 2023)