Additional well-designed, placebo-controlled clinical trials would be required to more fully characterize its pharmacokinetics, safety profile, and potential clinical relevance in human subjects
An earlier double-blind RCT by Arjinpathana and Asawanonda published in the Journal of Dermatological Treatment in 2012 (n=60, oral GSH 500 mg/day for 4 weeks) found that oral glutathione produced a modest skin-lightening effect in sun-exposed areas versus placebo, establishing the foundational clinical signal for the oral route
Salmonella-innovative targeting carrier: loading with doxorubicin for cancer treatment
Bajt ML, Ho YS, Vonderfecht SL, Jaeschke H
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Others exclude them entirely