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The SURPASS-3 study was set up to investigate the efficacy and safety of tirzepatide versus a titration of the basal insulin degludec inadequately controlled by an oral therapy of T2D by metformin with or without an SGLT2 inhibitor comedication for 52 weeks (72)

Figure 6 Clinical Trial Findings: Quantification of Cytokines Levels Within Granuloma Supernatants of PBMCs Infected In Vitro With BCG in T2DM Subjects Levels of cytokines: IL-6, IL-10, IFN- and TNF- were quantified from the supernatants of in vitro granulomas generated from PBMCs isolated from T2DM subjects at pre- and post- L-GSH/or placebo supplementation