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General: Limitations of Use: This drug has not been studied in patients with history of pancreatitis
Updated March 15, 2026
00:06:39 Sara Klockars: Right, right
Contraindications : It should not be used in patients with a history of medullary thyroid carcinoma, MEN2, severe gastroparesis, pregnancy, or uncontrolled GI disease
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Persistent symptoms despite 2 weeks of PPI therapy: If omeprazole or similar medications are not controlling your heartburn, your provider may want to perform an endoscopy or pH monitoring to evaluate for complications like Barrett esophagus or esophageal stricture
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