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Its also advised against for individuals with active or suspected cancer or those with Wilsons disease, a rare genetic disorder related to copper metabolism

Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis

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produces a more favorable prolonged pressor response compared to phenylephrine, accompanied by a dose-dependent maintenance or increase of in heart rate, stroke volume & cardiac output when administered to patients under general anesthesia (Table 1)(Meng L et al, 2011