Originally developed for diabetes management, these drugs, popularized under brand names such as Ozempic, Wegovy, Mounjaro, and Zepbound, are redefining how we think about obesity, metabolic health, and even chronic disease prevention
Severe hyponatremia can progress to seizures or coma
The SURPASS-3 study was set up to investigate the efficacy and safety of tirzepatide versus a titration of the basal insulin degludec inadequately controlled by an oral therapy of T2D by metformin with or without an SGLT2 inhibitor comedication for 52 weeks (72)
Yoshida, A., and Moritoki, K., Nitrogen sparing action of methionine and threonine in rats fed a protein free diet, Nutr
Because GLP-1 medications make you feel full more quickly, its easy to leave the protein on your plate if you start with other foods
and in older individuals, hypothyroidism accelerates cognitive decline while hyperthyroidism increases anxiety and sleep disturbances ( The thyroidbrain axis represents a complex system of bidirectional communication between endocrine and neural networks