Prednisone may cause several side effects, especially with long-term use at higher doses
Data availability The EHR database used in this study were obtained from TriNetX ( Abbreviations GLP-1RAs: Glucagon-like peptide-1 receptor agonists T2DM: Type 2 diabetes mellitus EHRs: Electronic health records SGLT2: Sodium-glucose cotransporter-2 DPP-4: Dipeptidyl peptidase-4 HR: Hazard ratios CI: Confidence intervals References Alfaris N, Waldrop S, Johnson V, Boaventura B, Kendrick K, Stanford FC (2024) GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review
And, results may vary depending on timing and current symptom flare-ups
Then the TMAO cardiovascular question, which is the one substantive open debate
Over time, that interest expanded into other areas, including muscle, tendon, ligament, and soft-tissue healing
Lipo-C: 1 mL once weekly (tirzepatide is potent enough that twice-weekly Lipo-C may not add significant benefit)