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Limitations of current models and the promise of organoids While mouse models have been invaluable for studying TGF- signaling, they often fall short in replicating human-specific conditions (Table 2)
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Finally, the analysis of the predicted metabolites revealed that AcM could enhance the production of microbial molecules related to lipid-metabolism, active metabolites and neurotransmitters (valeric/isovaleric acid, azelate, azelaic acid, anandamide C20:4, carnitine and undecanedioic acid), metabolism of vitamins and nucleotides/nucleosides, whilst possibly depleting inosine
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