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The cells were incubated with the respective probes in growth medium for the indicated time

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[2] [4] The mucosa of the lip may become fissured (cracked), crusted, ulcerated or atrophied

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The synthesis started with pyrimidine 82 , which was exposed to a microwave-assisted reaction with (5-methyl-1,3,4-thiadiazol-2-yl)methanamine hydrochloride, yielding intermediate 83

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