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Lyophilization is a sophisticated freeze-drying process where water is removed from the peptide under vacuum
W.LadensteinR.SchfferJ.GallayO.HuberR
The metformin dosage was calibrated and adjusted according to body surface area with reference to the human equivalent dose (1000 mg/day)
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For example, alcohol causes the malfunctioning of biological signalling molecules by increasing the amount of ROS, while decreasing the levels of cellular antioxidants (267), leading to the accumulation of acetaldehyde (268) and causing cell apoptosis as a result of it inducing mitochondrial dysfunction (269)
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