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The high expression of ACMSD in the kidney and liver offers the therapeutic potential of ACMSD inhibitors, such as TES-991 and TES-1025, for renal and hepatic dysfunction
If youre okay with a weekly injection and want more predictable weight loss, injectable semaglutide could be a better option
Stat Med (2009) 28(25):3083107
Additionally, patients with severe sulfur or salicylate intolerancesoften seen in severe MCASshould consult their provider before starting, as cruciferous extracts may trigger sensitivities in highly reactive individuals
Weight of evidence: Overall evidence is LowModerate : robust mechanistic plausibility and diverse preclinical benefits
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