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With the aid of tyrosinase-related protein 2, dopachrome is then converted into 5,6-dihydroxyindole-2-carboxylic acid (DHICA), and 5,6-dihydroxyindole (DHI) (Olivares et al., 2001)

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Patients on chronic corticosteroids may require dose adjustments or careful monitoring of IGF-1 levels to ensure sermorelin is having the desired effect