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As Hurley scoring does not allow a precise assessment of disease severity or improvement with drug treatment, there is a broad consensus to use the International Hidradenitis Suppurativa Severity Score System (IHS4), which is a validated score suitable for graded assessment of HS severity [19]
Melanocortin agonism stimulates melanocytes, and a related report describes eruptive nevi a sudden crop of new moles associated with an -MSH analog, exactly the kind of pigment-cell proliferation one would predict from over-stimulating this pathway
It should be noted, however, that rare hypersensitivity reactions can occur
& Shimada, S
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