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However, whether autophagic flux is blocked remains yet to be fully elucidated, as the elevated LC3-II/LC3-I ratio may reflect either autophagic activation or impaired flux leading to autophagosome accumulation (130)

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The explosion of GLP-1 weight loss treatments has blurred the lines between specialties, and many psychiatric providers are fielding patient requests or considering adding weight management to their practice

doi: 10.1016/0031-9384(90)90144-S 30 CohenITSherwinBBFlemingAS

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