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Reference: Nutritional priorities to support GLP-1 therapy for obesity: a joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society Mozaffarian, Dariush et al

The most common gastrointestinal side effects include nausea (very common, affecting 1/10 patients), diarrhoea, vomiting, abdominal pain, and decreased appetite

Furthermore, SSTRs, particularly SSTR5, are highly expressed in intestinal L-cells that secrete glucagon-like peptide-1 (GLP-1) and K-cells that secrete glucose-dependent insulinotropic polypeptide (GIP)

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