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They do work, but some people stop taking them due to side effects, which include nausea, vomiting, diarrhea, or constipation

21 Differential Diagnosis Misdiagnosis at initial biopsy is common in our experience and that of others and may be the basis for inadequate initial local therapy that underlies the high rates of local recurrence of this neoplasm

On the key cardiac measure, change in ejection fraction, the difference was 0.04 percentage points with a p-value of 0.97

& Uribarri, J