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Patients should follow the dose escalation schedule given below

Avoiding high-fat and high-fiber foods during the first 23 weeks, then reintroducing them gradually, allows your digestive system to adapt without overwhelming it

Dose splitting addresses both problems simultaneously: lower peaks reduce side effects, and higher troughs maintain appetite suppression throughout the week

How many days does a B12 shot last

These sequence changes reduce binding to IGF-binding proteins (IGFBPs) and support sustained availability in experimental models

The medication helps control appetite and slows digestion, but your food choices determine how well that support works