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The docking conformation of Arbutin_a shows very little difference from the MD-stable conformation, indicating that arbutin can stably bind to mTYR in this conformation

It's also not available as an FDA regulated drug, or even considered to be sellable for human use

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These findings are consistent with the results of CVOTs conducted for different GLP-1RAs

It can alleviate acne and dry skin, promoting a rejuvenation process that enhances overall skin health

10.1074/jbc.M116.740324 182 XuX.LongH.XiB.JiB.LiZ.DangY.et al (2019)