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This nanoplatform restores hepatic responsiveness to insulin by scavenging mitochondria-generated ROS via platinum particles, activating protein kinase pathway, and increasing cellular nutrient uptake and oxidation

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However, native GLP-1 has a short half-life of approximately 23 min, limiting its therapeutic potential [12]

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Sustainable weight management still depends on diet, physical activity, sleep, and treatment of contributing conditions when present

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It is available in many foods, and bioavailability from dietary sources is much higher (54%87%) than from oral supplements (14%18%) (48)

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