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It also slows gastric emptying, meaning food remains in the stomach longer, which contributes to increased satiety and reduced calorie intake
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These combined effects explain why tirzepatide produces substantial weight lossup to approximately 21% of body weight in adults without diabetes at the 15 mg dose in clinical trials, with somewhat lower averages in people with type 2 diabetesalongside improvements in hemoglobin A1c levels
"Adipose tissue quality in aging: how structural and functional aspects of adipose tissue impact skeletal muscle quality." Nutrients 11.11 (2019): 2553
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