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However, in one of the studies included in this meta-analysis a double-blind, controlled study in 56 adults diagnosed with MDD curcumin treatment (~880 mg/day of curcuminoids) for eight weeks was no more effective than placebo in reducing self-reported depression- and anxiety-related symptoms (101)

Hum Mol Genet 17:2790802

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it changes the regulatory access question

Critically, no effects on hematocrit or red blood cell counts were observed at any dose confirming that the peptides tissue-protective activity is fully dissociated from erythropoietic activity

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