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In the A Study of Tirzepatide [LY3298176] in Participants with Type 2 Diabetes (SURPASS-2) trial, tirzepatide (5 to 15 mg) was superior to 1.0 mg of semaglutide in improving both HbA1c and body weight [5], in contrast to our results
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What works at 0.25 milligrams may not work at 1.0 milligrams or higher
EVIDENCE SECTION: Cite STEP trials, SELECT trial (cardiovascular benefit), professional guidelines (AACE (American Association of Clinical Endocrinology), Endocrine Society), and FDA approval information
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