We just need to make sure its moving in the right direction
Finally, the biology of non-response and therapeutic resistance - including the role of gut microbiome composition, adipose tissue dysfunction phenotypes, and genetic determinants of drug metabolism - represents a frontier for translational investigation to improve patient outcomes
Caroline Fontana
Introduction Most people who start a GLP-1 medication notice nausea, reduced appetite, or slower digestion
What This Means for Our Practice Seven additional Phase 3 trials are expected in 2026, evaluating retatrutide across obesity, type 2 diabetes, sleep apnea, chronic low back pain, and MASLD
Lee JK, Shin JH, Gwag BJ, Choi E-J (2015) Iron accumulation promotes TACE-mediated TNF- secretion and neurodegeneration in a mouse model of ALS