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10.1038/35041687 Nature 7 FujimotoC.IwasakiS.UrataS.MorishitaH.SakamakiY.FujiokaM.et al (2017)
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Glutathione is a compound that is actually made by the body to protect it from these free radicals
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This indicates that stimulating GSH production, which has been shown to prevent degeneration of RPE cells 70 , could potentially serve as an intervention strategy to combat ROS in maturing mouse retinas with RP where all rods have degenerated
The activation of the glyoxalase system is precisely synchronised with the ascorbateglutathione (AsA-GSH) cycle, which includes APX, GR, MDHAR, and DHAR, to maintain redox homeostasis and mitigate oxidative damage
