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This hydrogel depot technology is easy to manufacture, injectable, and exhibits excellent biocompatibility, enabling months-long-acting treatments with the potential to improve management of diabetes and weight
For instance, NLY01, a long-acting PEGylated GLP-1RA with an extended half-life [41], effectively mitigates retinal ganglion cell (RGC) apoptosis induced by elevated intraocular pressure, a process mediated by a well-defined inflammatory cascade [44]
165 In addition, the machinery that inhibits autophagy involves Atgs
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