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LDLR promotes autophagy-mediated cisplatin resistance in ovarian cancer associated with the PI3K/AKT/mTOR signaling pathway

The NAD + cofactor binds at the C-terminal end of the parallel beta strands in the N-domain, lying in the cleft between the N and C-domains

The dissected gonads were washed three times for at least 30 min (10-min interval) with 1x PTW/0.5%BSA solution and incubated the dissected gonads in the 1x PTW/0.5% BSA solution containing the fluorescence-conjugated secondary antibodies for 1-2 hours at room temperature

Side effects are more likely in people with high blood pressure, heart disease, rhythm problems, digestive or kidney disease, diabetes on insulin or sulfonylureas, a history of medullary thyroid cancer, or those taking MAOIs, certain antidepressants, seizure drugs, or opioids