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Cellular capacities for ROS elimination are limited in Nrf2 -null mice ( Nrf2 -null mice tend to spontaneously develop various inflammatory disorders, including glomerulonephritis, immune-mediated hemolytic anemia, and multi-organ autoimmune inflammation (Yoh et al., 2001

Ruksiriwanich et al.[189] showed that the ability of rice bran oil to promote melanin synthesis in B16F10 cells may be related to iron, zinc, and unsaturated fatty acids