NIH ODS Fact Sheet for Health Professionals: Vitamin B12 (updated 2024)
Despite the substantial conformational dynamics when bound to AMY 3 R, Cagri maintains the bypass conformation across the motions, likely arising from the consistent TMD and linker interactions between RAMP3 and CTR that enable robust engagement of residues within the Cagri bypass motif
Vitamin B12 can be given via injection or high doses of oral medication to increase the stores of B12 in the body
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This method is chosen for its potential to bypass the digestive system, ensuring more efficient absorption of the vitamin into the bloodstream
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