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LEADER Publication Committee on behalf of the LEADER Trial Investigators
J., & O'Keefe, J
Tirzepatide enhances fat loss more effectively than Ozempic because it targets not only GLP-1 receptors but also GIP (glucose-dependent insulinotropic polypeptide) receptors
Improved liver enzymes: ALT and AST (markers of liver inflammation) typically decrease with treatment
This discrepancy between results in animal models and clinical studies may partly be due to myocardial insulin resistance in severely failing hearts and the use of beta-blockers [21]
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