Released by the anterior pituitary gland in pulsatile bursts primarily during deep sleep GH governs fat metabolism, muscle protein synthesis, cellular repair, and IGF-1 production in the liver
However, markedly elevated levels without supplementation may warrant GP review to exclude underlying conditions such as haematological disorders, liver disease, or renal impairment
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The studies showed that treatment reduced body weight gain by over 50% compared to controls over a 19-day period, with increased lipolytic activity specifically in adipose tissue deposits
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Patients have also occasionally experienced thyroid tumors