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It is sold as a research chemical NNMT inhibition has broad implications : NNMT is involved in multiple metabolic pathways beyond NAD+, including methylation balance, polyamine metabolism, and one-carbon metabolism

This deficiency can be caused by poor dietary consumption, a breakdown in the digestive process, or from taking certain medications that make it difficult to absorb B12 (such as antacids)

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Studies show it has been observed to stimulate the breakdown of stored fat cells and inhibit new fat formation without the effects on blood sugar or tissue growth seen with full growth hormone